Amyris
AMYRIS, INC. (Form: 4, Received: 10/12/2011 17:33:44)
FORM 4
[ ] Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).         
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES
                                                                                  
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Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public
Utility Holding Company Act of 1935 or Section 30(f) of the Investment Company Act of 1940
                      

1. Name and Address of Reporting Person *

Melo John
2. Issuer Name and Ticker or Trading Symbol

AMYRIS, INC. [ AMRS ]
5. Relationship of Reporting Person(s) to Issuer (Check all applicable)

__ X __ Director                      _____ 10% Owner
__ X __ Officer (give title below)      _____ Other (specify below)
President and CEO
(Last)          (First)          (Middle)

C/O AMYRIS, INC., 5885 HOLLIS ST., SUITE 100
3. Date of Earliest Transaction (MM/DD/YYYY)

10/10/2011
(Street)

EMERYVILLE, CA 94608
(City)        (State)        (Zip)
4. If Amendment, Date Original Filed (MM/DD/YYYY)

 
6. Individual or Joint/Group Filing (Check Applicable Line)

_ X _ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)
2. Trans. Date 2A. Deemed Execution Date, if any 3. Trans. Code
(Instr. 8)
4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)
5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)
6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V Amount (A) or (D) Price
Common Stock   10/10/2011     M (1)    20000   A $0.28   20000   I   (2) John and Mary Melo Family Foundation   (2)
Common Stock   10/10/2011     S (1)    20000   (3) D $17.216   (4) 0   I   (2) John and Mary Melo Family Foundation   (2)
Common Stock                  23000   D    

Table II - Derivative Securities Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities)
1. Title of Derivate Security
(Instr. 3)
2. Conversion or Exercise Price of Derivative Security 3. Trans. Date 3A. Deemed Execution Date, if any 4. Trans. Code
(Instr. 8)
5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)
6. Date Exercisable and Expiration Date 7. Title and Amount of Securities Underlying Derivative Security
(Instr. 3 and 4)
8. Price of Derivative Security
(Instr. 5)
9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Stock Option (Right to Buy)   $0.28   10/10/2011     M   (1)       20000      (5) (6) 1/18/2017   Common Stock   20000   $ 0   40000   I   (7) John and Mary Melo Family Foundation   (2)
Stock Option (Right to Buy)   $0.28                      (5) (6) 1/18/2017   Common Stock   553730     553730   D    
Stock Option (Right to Buy)   $0.28                      (5) (6) 1/18/2017   Common Stock   18539     18539   I   (8) Melo Family 2010 Distribution Trust   (8)
Stock Option (Right to Buy)   $0.28                      (5) (6) 1/18/2017   Common Stock   9936     9936   I   (9) Descendant's Trust #1   (9)
Stock Option (Right to Buy)   $0.28                      (5) (6) 1/18/2017   Common Stock   9936     9936   I   (10) Descendant's Trust #2   (10)
Stock Option (Right to Buy)   $0.28                      (5) (6) 1/18/2017   Common Stock   9936     9936   I   (11) Descendant's Trust #3   (11)
Stock Option (Right to Buy)   $0.28                      (5) (6) 1/18/2017   Common Stock   26653     26653   I   (12) Melo Renewal Trust   (12)

Explanation of Responses:
( 1)  ***RULE 10B5-1 TRADING PLAN TRANSACTION: EACH OF THE FOREGOING OPTION EXERCISE AND STOCK SALES WAS EFFECTED PURSUANT TO A RULE 10B5-1 TRADING PLAN ADOPTED BY THE JOHN AND MARY MELO FAMILY FOUNDATION ON SEPTEMBER 9, 2011.***
( 2)  The shares are directly beneficially held by the John and Mary Melo Family Foundation (the "Foundation"). Mr. Melo is the President of the Foundation and, as such, has voting and/or investment power over the securities held by the Foundation.
( 3)  Represents the aggregate of sales effected on the same day at different prices pursuant to the plan in footnote (1).
( 4)  Represents the weighted average sales price per share. The shares sold at prices ranging from $16.66 to $17.55 per share. Full information regarding the number of shares sold at each price shall be provided upon request to the staff of the U.S. Securities and Exchange Commission, the Issuer, or a security holder of the Issuer.
( 5)  Immediately exercisable.
( 6)  The stock option vested as to 1/5th of the total number of shares subject to the option on October 23, 2007, and thereafter vested and shall vest as to 1/60th of the total number of shares subject to the option in equal monthly installments.
( 7)  This stock option was previously reported as directly beneficially owned by Mr. Melo, but was contributed on September 1, 2011 to the Foundation.
( 8)  This stock option was previously reported as directly beneficially owned by Mr. Melo, but was contributed on March 18, 2010 to the Melo Family 2010 Distribution Trust.
( 9)  This stock option was previously reported as directly beneficially owned by Mr. Melo, but was contributed on April 4, 2011 to the Descendant's Trust #1.
( 10)  This stock option was previously reported as directly beneficially owned by Mr. Melo, but was contributed on April 4, 2011 to the Descendant's Trust #2.
( 11)  This stock option was previously reported as directly beneficially owned by Mr. Melo, but was contributed on April 4, 2011 to the Descendant's Trust #3.
( 12)  This stock option was previously reported as directly beneficially owned by Mr. Melo, but was contributed on April 4, 2011 to the Melo Renewal Trust.

Reporting Owners
Reporting Owner Name / Address
Relationships
Director 10% Owner Officer Other
Melo John
C/O AMYRIS, INC.
5885 HOLLIS ST., SUITE 100
EMERYVILLE, CA 94608
X
President and CEO

Signatures
/s/ John Melo by Nicholas Khadder, Attorney-in-Fact 10/12/2011
** Signature of Reporting Person Date


Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
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